Thursday, 24 September 2015

Pharma High yield


Mechanism of Action
1-DNA Dependent RNA Polymerase– Rifampcin
2- RNA Dependent DNA Polymerase– Zidovudine
3-Proetin Synthesis Blocker– Erythromycin,     Chloramphenicol & Tetracycline
4-ACE Inhibitor– Captopril
5-Ca Channel Blocker– Nifedipine, Diltiazem
6-COX Inhibitor– Asprin
7-GABA Facilitator– Benzodiazepines
8-Antimetabolites– Methotrexate
9-Loop Diuretics– Frusemide
10-High Ceiling Diuretics– Spironolactone
11-Alteration of bacterial DNA– Choloroquine
12-Inhibition of Viral replication– Amantidine, Acyclovir
13-H1 blocking agent– Mepyramine, Loratadine
14-H2 Blocking agent– Rantidine, Cimetidine, Famotidine, Cyprohaptidine
15-Proton Pump inhibitor– Omeprazole
16-DNA Metabolism Inhibitors– Quinacrine (Mepacrine)
17-Spindle Poison– Vinca, Griesofulvin
18-Folic acid synthesis inhibitor– DDS
19-GABA Inhibitor– Sodium Valproate
20-DNA Synthesis Prevention – Nalidixic Acid
21-Prostaglandin Synthesis Inhibition– Oxyphenbutazone, Ibuprofen
22-Mycolic acid synthesis inhibition– INH
23-Folic acid antagonist- MTX, PAS, DDS & Primethamine
24-Desruption of DNA structure– MNZ
25-Inhibition of cell wall synthesis– Beta lactam antibiotics (penicillin)
26-Release of nor epinephrine– Ephedrine
27-Ergosterol Biosnythesis Inhibitors– Clotrimazole, Miconalzole, Ketoconazole
28-Ach esterase inhibitors– Physostigmine, Neostigmine, Edrophonium, Metrifonate
29-Reverse Transcriptase Inhibitors– Stavudine, zidovudine
30-Inhibition of HIV Protease– Amepranavir
31-DNA Gyrase Inhibitor– Cinoxacin
32-Inhibition of DNA Polymerase-Gossypol
33-NMDA Receptor Antagonist– Amantadine, Ketamine, Dextromethorphan, Memantine & Nitrous Oxide
34-DNA intercalating agent– Daunorubicin, Doxorubicin, Ellipticin & Ethidium Bromide
35-Antim mitotic agent– Amphethenile
36-Alkylating agent- Thiotepa
37-Alpha receptor antagonist- Phentolamine
38-Beta receptor antagonist- Propanolol, Aplrenolol
39-Alpha receptor agonist- Norepinehrine
40- Beta receptor agonist- Isoproterenol & Salbutamol
41-DNA Adduct Formation– Procarbazine
42-Carbonic anhydrase inhibitor- Acetazolamide
43-Phosphodiestrase Inhibitor- Theophylline
44-Thrombin action prevention- Heparin
45-Xanthine oxidase inhibitor- Allopurinol
46-Cholinergic Blockade- Ipratropium
47-Adenosine Deaminase inhibitor- Crisnatapase
48-Immunomodulation– Imiquimod
49-Amino acid transfer interference– Econazole
50-Mast Cell Stabilization– Ketosifen

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