Saturday, 15 August 2015

Prognostic factors in neuroblastoma:

Prognostic factors in neuroblastoma:

Age – Less than 1 year have good prognosis
Stage – I and II have good prognosis
Ploidy – Triploid and hyperploid tumours have good prognosis
Cytogenetics – Chromosome 1 / Chromosome 14 deletions have worse prognosis
n-myc oncogene amplification – associated with bad prognosis
Trk A expression – high levels are associated with favourable outcome

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