Thursday, 27 August 2015

Insulin

INSULIN

Number of aa in insulin 51✔

A chain has 21aminoacids✔
B chain has 30aminoacids✔

No of disulphide bonds-3✔

Linkage b/w cystine-cystine✔

Exogenous insulin no c peptides✔

Endogenous insulin has both c peptides and insulin in equal ratio 1:1✔

MINERAL STORED WITH INSULIN IN BETA
CELL GRANULES zinc✔

MINERAL WHICH INCREASES INSULIN
SENSITIVITY AND ALLEVIATES INSULIN
RESISTANCEChromium✔

Noble price for isolation of insulinBANTING & BEST✔

Nobel price for sequencing of insulin structureSANGER✔

Insulin gene11 chrmosome
Insulin receptor gene19✔

insulin is degrade by glutathione insulin transhydrogenase aka insulinase✔

half life of inssulin? 5 to 10mins✔

pork insulin differs from human by 1 aa..bovine insulin by 3 aminoacids✔

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