Thursday, 6 August 2015

Derma high yield notes

1) Most common organism causing tinea- Trichophyton rubrum

2) Most common organism causing tinea capitis- Trichophyton violaceum

3) Most common cranial nerve involved in Hansens- facial

4) Most common nerve taken for nerve biopsy in Hansens- radial cutaneous (upper limb), sural (lower limb)5

) Most common cause of mononeuritis multiplex - Hansen (India), DM (world)

6) Most common cause of ENL- LL> BL7) Most common cause of a negative  Slit skin smear in Hansen- neural leprosy

8)  Cause of Type 1 reaction- BB> BT> BL

9)  DOC for type 1 and type 2 reaction- steroids

10) DOC for chronic, recurrent ENL- thalidomide

11) Most common side effect of dapsone- hemolytic anemia

12) Most common side effect of clofazimine- pigmentation

13) Most common cause of inverted saucer lesion- borderline leprosy

14) Most common cause of leonine facies- LL

15) Earliest sensation lost- temperature

16) Most common Hansen- Borderline Tuberculoid

17) Commonest site for Fixed drug eruption (FDE)- lips

18) DOC for tinea - terbinafine

19) DOC for tinea capitis- griseofulvin

20) Most common type of onychomycosis – Distal and lateral onychomycosis (In HIV, the most common type is proximal subungual onychomycosis and superficial whiteonychomycosis)

21) DOC for sporotrichosis- itraconazole> potassium iodide

22) Most common cause of reactive arthritis- Chlamydia> Shigella

23) Most common Psoriatic arthritis- oligoarticular, asymmetric.

24) DOC for psoriatic arthritis- Methotrexate

25) DOC for arthritis mutilans- etanercept

26) DOC for guttate ps- antibiotics

27) DOC for erythrodermic psoriasis- Methotrexate

28) DOC for pustular psoarisis- Acitretin

29) DOC for early mycosis fungoides- Electron beam therapy > Phototherapy

30) Most common type of pemphigus- pemphigus vulgaris

31) Rarest type of pemphigus- pemphigus vegetans

32) DOC for Dermatiis herpetiformis- Dapsone

33) Most classical joint involved in Psoriatic Arthritis- DIP

34) Most common cause of non bullous impetigo- strepto> staph

35) Most common cause of bullous impetigo- staph

36) Most common underlying disease in kaposis varicelliform eruption - atopic dermatitis

37) Most common site of adult atopic dermatitis- ante cubital fossa

38) Most common site of pediatric atopic dermatitis- cheek

39) Most common cause of cumulative Irritant contact dermatitis- detergents, Wet work

40) Most commonest cause of Allergic contact dermatitis-nickel

41) Most common cause of air borne contact dermatitis- parthenium

42) DOC for air borne contact dermatitis - azathioprine

43) Most common layer of epidermis for lamellar body presence- granular layer

44) Most common layer for synthesis of vitamin D ( Also same answer for presence of langerhans cells)- spinous layer

45) Thickest layer of epidermis- corneum

46) Thinnest layer of epidermis- granular

47) Most common cause of acute paronychia- staph

48) Most common cause of chronic paronychia-candida

49) Most common syphilis transmitted by sexual route- primary

50) Most common syphilis transmitted from infected mother- secondary

51) Most infectious lesion in syphilis- mucous patches

52) Most sensitive test in syphilis- Enzyme Immunoassay> TPPA > FTA-abs

53) Most specific test in syphilis- TPPA> TPHA

54) DOC for chancroid- azithro

55) DOC for LGV and donovanosis- doxy

56) DOC for syphilis in pregnancy- penicillin

57) DOC for urethral discharge and cervical discharge (syndromic management)- azithro+ cefixime

58) DOC for vaginal disch (syndromic management)- fluconazole + secnidazole/metro/tinidazole

59) DOC for bubo (syndromic management)- azithro+ doxy

60) DOC for genital ulcer (syndromic management)- if vesicle - acyclovir,  if not azithro+ benzathine penicillin

61) DOC for neurosyphilis- crystalline aqueous penicillin

62) DOC for penicillin allergy in syphilis- doxy

63) DOC for penicillin allergy in syphilis in pregnancy- desensitization

64) DOC for penicillin allergy in neurosyphilis- desensitization

65) DOC for Impetigo herpetiformis- steroids

66) Investigation of choice in primary syphilis- dark ground illumination

67) Most common cutaneous TB- lupus vulgaris (In children, it is Scrofuloderma)

68) Test of choice for lupus vulgaris- biopsy

69) Most common organism for p versicolor now in India- Malassezia globosa

70) Most common  internal organ inv in leprosy- testis

71) Organ never inv in leprosy- uterus> CNS72) Sensation never lost in hansens- propioception, vibration

73) DOC for Post herpetic neuralgia- Gabapentin

74) Most characteristic of LP on histopathology- basal cell degeneration

75) Best time to read patch test- 4 days

76) Commonest drug for FDE- sulphonamides

77) Commonest cause of Erythema Multiforme- HSV

78) Commonest cause of SJS/TEN- drugs (NSAIDS, anti epileptic,  sulphonamides,  penicillin)

79) DOC for scabies- 5% permethrin

80) DOC for scabies in pregnancy- 5% permethrin

81) DOC for nodular scabies- permethrin+ steroids

82) DOC for nerve abscess- I and D

83) DOC for nodulocystic acne- oral isotretinoin

84) DOC for hormonal acne- OCP with  drosperinone+ estrogens

85) DOC for pediculosis corporis- disinfection of clothes

86) DOC for head louse- 1% permethrin

87) DOC for norwegian scabies- ivermectin

88) Most common shape of burrow in  scabies- S-shaped

89) Most common and earliest manifestation of tuberous sclerosis- ash leaf macule> adenoma sebaceum

90) Earliest manifestation of congenital syphilis- snuffles

91) Best blood test for congenital syphilis- FTA-ABS IgM

92) Most common site for morphoea- limbs

93) Most common cause for salt and pepper skin pigmentation- scleroderma

94) Most common cause of acanthosis nigricans- obesity

95) Most severe form of psoriasis- Von zumbusch

96) Most common melanoma-  superficial spreading melanoma

97) Poorest prognosis in melanoma- nodular

98) Most common type of BCC- noduloulcerative

99) Most common cause of hypopigmented, scaly patches on cheek of children- Pityriasis alba

100) Most common cause of hypopigmented, nonscaly, atrophic patches on cheek of endemic area children- indeterminate hansens

101) Investigation of choice for neurosyphilis- CSF-VDRL

102) Most common type of oral LP- reticulate / white lacy pattern

103) DOC for localised alopecia areata- intralesional steroids

104) Most effective drug in alopecia areata- contact sensitizers

105) commonest autoimmune association in vitiligo- thyroid

106) Commonest agent for leucoderma- paratertiary butyl phenol (PTBP)

107) Commonest agent for hair dye allergic contact dermatitis- paraphenylene diamine (PPD)

108) Commonest agent for footwear allergic contact dermatitis- Mercaptobenzothiazole (MBT)

109) Investigation of choice for Air borne contact dermatitis- photo patch test

110) Commonest extra genital site for primary chancre- lips

111) Commonest cause of recurrent blisters on genitals (healing with hyperpigmentation- FDE) ( if not then herpes genitalis)

112) Commonest vitiligo- Vitiligo vulgaris

113) Most common cause of erythema nodosum- Strepococcus.

114) Most common cause of patchy alopecia- Alopecia areata

115) DOC for rosacea- Metronidazole (topical), Doxy (Oral)

116) Commonest site for primary syphilis chancre- Coronal sulcus

117) First test to become positive in primary syphilis- FTA-Abs

118) Characteristic nail change in LP- Pterygium

119) Commonest cause of apple jelly nodules- Lupus vulgaris

120) Commonest cause of hypopigmented, minimally scaly macules and patches on chest and back of young adults- P. versicolor

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