Friday, 27 June 2014

CD Markers

CD1a, CD207: Langerhan cell histiocytosis cells
CD2, CD3, CD4, CD5, CD7, CD8: T cells
CD10: Early pre-B cells (immature B cells)
CD11c, CD25, CD103, CD123: Hairy cell leukemia cells
CD13, CD33, CD117: Myeloid cells
CD14, CD64: Monocytic cells (positive in AML-M4 and AML-M5)
CD15: Reed-Sternberg cells, neutrophils
CD16, CD56: Natural killer cells
CD19, CD20, CD21, CD22 : B cells
CD23 and CD5 : Chronic lymphocytic leukemia/small lymphocytic lymphoma
CD23 negative and CD5 positive: Mantle cell lymphoma cells
CD30 and CD15: Reed-Sternberg cells
CD30 positive and CD15 negative: Anaplastic large cell lymphoma cells
CD31: Endothelial cells (positive in angiosarcoma)
CD33: Myeloid cells and precursors
CD34: Stem cells (also positive in angiosarcoma)
CD41, CD61: Megakaryocytes and platelets (positive in AML-M7)
CD45 : All leukocytes (except Reed-Sternberg cells!)
CD45 RO: Memory T cells
CD45 RA: Naive T cells
CD68: Histiocytes (positive in malignant fibrous histiocytosis)
CD99: Ewings sarcoma cells
CD117: Gastrointestinal stromal tumor (GIST) cells, mast cells (positive in mastocytosis), myeloid cells

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