Saturday, 10 May 2014

Alcohol

In alcohol intoxication, motor incoordination and judgement errors occur at blood alcohol
levels of
a.  30-80 mg/dL
b.  80-200 mg/ dL
c.  200-300 mg/dL
d.   More than 300 mg/ dL
Ans. (b)

Ethanol intoxication
Measurement of levels in exhaled air is the primary method of assessing the level of intoxication.
Blood alcohol levels are necessary to confirm the presence or absence of alcohol intoxication.
Blood ethanol levels of 20-30 mg/dL
An increased reaction time, diminished fine motor control, impulsivity, and impaired judgment
become evident when the concentration of ethanol in the blood is 20-30 mg/dL.
Blood ethanol levels of about 80 mg/dL
Blood levels of 80 mg/dL are associated with slurred speech, incoordination, unsteady gait, and
potential impairments of attention.
Levels between 80 and 200 mg/dL
Levels between 80 and 200 mg/dL are associated with mood lability and cognitive deficits,
potentially accompanied by aggressiveness, and anterorgrade amnesia (an alcoholic blackout).
Levels >200 mg/d
Blood ethanol levels >200 mg/dL can produce nystagmus and unwanted falling asleep.
Levels of 300 mg/dL and higher
Levels of 300 mg/dL and higher can produce failing vital signs, coma, and death.  In fatal cases,
the average concentration is about 400 mg/dL, although alcohol-tolerant individuals often can
withstand comparable blood alcohol levels.
Acute Ethanol Intoxication. Goodman & Gilman's The Pharmacological Basis of
Therapeutics, 12e > Chapter 23. Ethanol and Methanol
K.S Narayana Reddy: The essentials of forensic medicine and toxicology.

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