Monday, 24 March 2014

Pharmacology

ALL RECENT DRUGS , YOU WILL EVER FIND ANYWERE

Vismodegib- adults with metstatic bcc . .
Vipazodone- major depressive disorder . .
Vemurafenib-- unresectable metastatic melanoma . .
Tocilizumab-- active systemic juvenile idopathic arthrtis . .
Ticagrelor-- acute coronary syn . .
Telaprevir& boceprevir-- genotype 1 HCV in adiots with compensated liver disease. .
Tafluprost -- open angle glaucoma . .
Sunitinib-- rcc ..
Ezogabine --- partial onset seizure in adults. .
Fidaxomicin -- adults for rx of clos diff assoc diarrhoea..
Glucarpidase -- delayed mtx clerance in case of renal failure .
Icatibant -- acute atrack of hereditary angioedema in adults ..
Indacaterol --- airway obstrucn in copd pt.
Ivacaftor -- cystic fibrosis in pt 6 yrs n above who have G551D mutatiin in CFTR gene.
Linagliptin -- type-2 DM .
RILPIVIRINE-- new NNRTI ..
RIVAROxaban- px for dvt in pt whi underwent knnee or hip replacement sx.

Brentuximab vedotin -- hodg lymphoma after failure of autologus stem cell transplant & sys anaplastic large cell lymphoma . Gvn IV .
Crizotinib -- small cell metstatic ca Ie anaplastic lymphoma kinase .
Eculizumab -- atypical HUS. N PResently being used for PNH.

EVErolimus-- prog neuroendocrine tumor of pancreas ie unresectable . .
Ulipristal acetate-- prog agonist/antag emergency contraceptive . .
Ustekinumab--- mod to severe plaque psoriasis . .

Vandetanib-- unresectanble thyroid ca . .
Vinorelbine-- vinka alkaloid . .
Zaleplon - new hypnotic that decreases sleep latency withiut distrb sleep architecture.

Zoledronic acid -- only once yrly osteoporosis rx apprvd for prev of fractures after hip fracture .. .
Ranolanzine &trimetazidine-- chr angina .
Torcetrapib -- inc hdl cholesterol . .
Tipranavir & darunavir -- new protease inh (hiv) . .
Tetrabenazine -- rx of chorea in huntingtons disease .
Tocilizumab - RA .
TESAMORELIN -- reduce abd fat in hiv inf pt . .
Naftigine -- antifungal .
Teriparatide -- osteoporosis .
Tapentadol -- mod to sev pain.
Telavanacin -- sim to vancomycin used for bth MRSA & MSSA .
PAlivizumab-- rsv . .
Palioeridone-- schizophrenia .
Oritavancin -- MRSA .
PAZOpanib-- adv rcc. .
Pegloticase - hyoeruricemia .
Pegvisomant - rx for acromegaly . .
Pemetrexed -- in combn with cisplastin for adv non small cell lung ca . .
Phosphiramidone- pul htn . .
Pitavastatin -- pri rx for hyoercholesterolemia n comb dyslipidemia . .
plerixafor -- to mobilize hematopoietic stem cells to bloodstream so that can be collected for autologous transpln in pt of nhl n MM

RANIBIzumab -- age related macular edema . .
Relcovaptan -- v1 antgnst of vasopressin . .
Romidepsin -- cutaneous t cell lymp . .
Rilonacept -- long term rx of cryopyrin ass periodic syn - CAPS

Romiplostim - ITP .
Rufinamide -- lennoaux gustat syn .

Sargramostim & molgramostim -- leucopenia .

Sermorelin & hexarelin -- pit dwarfism . .
Silodosin -- BPH .
Spinosad -- tooical rx of head lice infestation .
Somatrem -- aids related wasting ..
Tadalafil - single daily dose for PAH .
OFatumumab -- CLL .
molsidomine -- nitrate with no tolerance ..
Acrivastine -- sec gen antihistamine. Also mizolastine, ebastine .
Natalizumab - multiple sclerosis . .
Fomivirsen -- CMV retinitis.
Frovatriotan, riza, zolmi, ele, almotriptan - acute atack of migraine. .
Ganaxolone -- absence seizure, catamenial epilepsy , inf spasm.
Erlotinib & geftinib-- nin small cell ca of lung ..
Glatiramer -- MS .
GOLIMUMAB-- once mnthly for RA , psoriatric arthritis & ank spondylitis . .
Granisetron & tropisetron -- chemo induced vomiting . .
Guanfacine -- ADHD .
Ibopamine -- peripheral domapine agonist for CHF & as a mydriatic .
Fedotozine -- diarrhiea dominanr IBS .

fingolimod -- relapsing mode of multiple sclerosis . .
Fesoterodine -- over active bladder .
Eribuoin mesylate -- mets breast cancer . .
Ibritumomab-- b cell Nhl .
Uradipil & indoramin -- hypertensive emergencies ..

Ivabradine-- chr stable angina by slowing heart rate . .

Ixabepilone -- with capecitabine for resistant breast cancer . .
Laronidase -- hurler disease .
Levoleucovorin -- for high dose mtx in osteosarcoma
Levosimendan -- CHF .
lisdexamfetamine dimesylate -- first n onky once daily for ADHD in adults .
Lorqcarbef -- carbacepham grp of b lactam antibiotic .
Maraviroc - hiv -1 .
Memantine -- slow prog of alzhemiers disease .
Methlynaltrexone bromide - opiod induce constioation .
Milnacipran -- fibromyalgia.
Miltefosine & sitamaquine- kala azar . .
Docosanol - herpes labialis .
Doloxifene & toremifene - breast cancer . .
Dornase alpha -- purulent pulm secretion in cystic fibrosis .
Dronabinol -- anti emetic . .
Dronedarone - anti arrythmic , similar to amidarone...
Drotrecogin alfa - severe sepsis in protein c pt . .
Efalizumab - psoriasis against cd 11
Eltrombopag -- ITP
DEXLANsoprazole -- ppi . .
Daptomycin - against streptogramin & linezolid resistant s. Aureus .
Daltroban & sultroban - anti agretory effects on platelets .
Cinacalcet -- osteoporosis .

Clevidipine butyrate -- ultra shirt acting CCB . .
DALFAMPRIDINE -- improve walking ability in multiole sclerosi pt .
Certolizumab- severe chrohns disease . .in adults . .

Cilomilast & roflumist -- bronchial asthma . .
Cabazitaxel - mets prostate ca .

Bimatoprost -- rx of hypotrichiosis . .
Berctant & poractant -- neonatal RDS . .
abatacept -- DMARD resistant RA .

Aliskiren, remikiren, enalkiren -- oral renin inh in htn rx . .
Alvimopan -- post op paralytic ileus ..
Apafant & lexipafant -- acute pancreatitis(PAF antagonist)

Atosiban -- delay premature labour . .
Avasimibe -- hypolipdemic drug .

Aviptadil - erectile dysfuntion.
Azilsartan medoxomil - arb for htn . .
Abobotulinumtoxin A - cervical dystonia in adults n to reduce d severity of abnrml head position n neck pain & temoorary improvmnt in mod to severe gkabellar lines . .

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