Thursday, 6 February 2014

Pregnancy

866. Question: During pregnancy the maternal blood volume increases by (DNB) Options:
(1 ) 5 - 10%
(2 ) 15 - 20%
(3 ) 50%✅
(4 ) 70%

Important facts about physiological changes during pregnancy !

1. Net weight gain – 11 kg (24 lbs)

2. Blood volume increases by 40-50%

3. Blood volume reaches max at – 30-32 weeks

4. Plasma volume increases by 50%

5. RBC volume increases by 20-30%

6. TLC increases with Neutrophilic leucocytosis

7. Total plasma concentration decreases

8. Total plasma protein increases

9. Albumin decreases

10. Globulin (IgA especially) slight increases

11. Fibrinogen levels increases

12. ESR increases

13. All clotting factors increases except – XI and XII

14. Platelet count decreases (gestational Thrombocytopenia)

15. Cardiac Output (Stroke volume increases ) by 40-50% by 30-34 weeks

16. Peripheral vascular resistance decreases

17. Diastolic BP decreases

18. Uterine blood flow increases

19. Plasma insulin level increases

20. S. Prolactin level increase

21. Vital capacity and Respiratory rate – constant

22. Renal plasma flow and GFR increases

23. All LFT remaind unchanged but ALP increases (due to Heat stable ALP from placenta)

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