Tuesday, 18 February 2014

CD molecules

CD1a, CD207: Langerhan cell histiocytosis cells

CD2, CD3, CD4, CD5, CD7, CD8: T cells

CD10: Early pre-B cells (immature B cells)

CD11c, CD25, CD103, CD123: Hairy cell leukemia cells

CD13, CD33, CD117: Myeloid cells

CD14, CD64: Monocytic cells (positive in AML-M4 and AML-M5)

CD15: Reed-Sternberg cells, neutrophils

CD16, CD56: Natural killer cells

CD19, CD20, CD21, CD22 : B cells

CD23 and CD5 : Chronic lymphocytic leukemia/small lymphocytic lymphoma

CD23 negative and CD5 positive: Mantle cell lymphoma cells

CD30 and CD15: Reed-Sternberg cells

CD30 positive and CD15 negative: Anaplastic large cell lymphoma cells

CD31: Endothelial cells (positive in angiosarcoma)

CD33: Myeloid cells and precursors

CD34: Stem cells (also positive in angiosarcoma)

CD41, CD61: Megakaryocytes and platelets (positive in AML-M7)

CD45 : All leukocytes (except Reed-Sternberg cells!)

CD45 RO: Memory T cells

CD45 RA: Naive T cells

CD68: Histiocytes (positive in malignant fibrous histiocytosis)

CD99: Ewings sarcoma cells

CD117: Gastrointestinal stromal tumor (GIST) cells, mast cells (positive in mastocytosis), myeloid cells.

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