Thursday, 5 February 2015

Bodies

1) BASOPHILIC STIPPLING
is ribosomal inclusions in RBCs
sideroblastic anemia, lead poisoning,
megaloblastic anemia, thalassemia, Arsenic
poisoning
2) PAPPENHEIMER BODIES
are iron deposits,
seen in SIDEROCYTES (siderocytes are
intraerythrocytic PERL'S PRUSSIAN BLUE
STAIN positive iron granules)
seen in----- sideroblastic anemia, hemolytic
anemia, and sickle cell disease
3) HEINZ BODIES
are precipitated hemoglobin seen with special stain (He for Heinz and He for Hemoglobin)
seen in --- G6PD deficiency anemia, drugs like primaquine and dapsone, fava beans
4) HOWELL JOLLY BODIES
are DNA remnants
seen in------sickle cell autosplenectomy;
severe hemolytic anemia, megaloblastic
anemia, hereditary spherocytosis, and
myelodysplastic syndrome (MDS).

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