Monday, 30 December 2013

Drugs and Adverse effects

Drugs specific adverse effect :::

Vanishing bile duct syndome -- chlorpromazine

Coronary steal phenomena -- dipyridamole and isoflurane

Toxic ambylopia --- ethambutol

Fatal myocarditis ---clozapine

Idiosyncratic hepatic necrosis in infant --sodium valproate

Pseudo porphyria -- piroxicam

Amotivational syndrome-- marijuana

Fetal aplasia cutis -- carbimazole/methimazole in pregnancy

Drug induced mysthenia gravis-- d- penicilamine

Salt and pepper fundus -- thioridazine

Blue halo effect -- sidenafil

Calciphylaxis -- warfarin use in hemodylasis pt

Livedo reticularis -- amantidine

DRESS ie drug related eosinophila and systemic symptoms -- allopurinol

Pseudolymphoma syndrome -- anticonvulsants

Delayed bone marrow suppresion --nitrosourea anticancer drugs

Predisposition to listeria infection -- fludarabine

FSGS --heroin

Peripheral neuropathy resembling motor neuron disease -- dapsone

Vacuolar myopathy -- vincristine

Acute hepatic necrosis in pregnancy -- tetracycline

Cytokine release syndrome --muromonab cd3

Hand foot syndrome -- capcitabine

Hemorragic cystitis -- ifosfamide

Haemolytic uremic syndrome -- mitomycine c

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