Saturday, 23 November 2013

Immuno Histo Chemical Markers


1. Tumor of epithelial origin ( carcinomas) - cytokeratin.
2. Tumor of mesenchymal origin ( sarcoma) - vimentin
3. Tumor of smooth muscle origin (leiomyoma) - smooth muscle actin, desmin
4. Tumor of skeletal muscle origin (rhabdomyomas) -desmin, myogenin
5. Tumor of vascular origin ( angiosarcoma) - factor 8, von willebrand factor, cd 31
6. Tumor of glial origin ( gliomas) - glial fibrillary acidic proteinGFAP
7. Tumor o f hepatic origin ( HCC) - heppar1, alphafetoprotein
8. Marker for stem cell - CD 34
9. B cells - CD 19, CD 20, CD 21, CD 22
10. T cells - CD 1,2,3,5,7
11. Pan B cell marker - CD 19
12. Pan T cell marker - CD 3
13. Classical Hodgkin's disease - CD 15, CD 30
14. Non classical Hodgkin's disease - CD 20, EMA
15. Hairy cell leukemia - annexin a1, cd 25, cd 103, cd11c
16. Mantle cell lymphoma - cycling D1
17. Apoptotic cells - annexin v
18. Seminoma - PLAP, HCG, oct 3/4, nanog
19. Yolk sac tumor - alpha veto protein
20. Choriocarcinoma - beta HCG

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