Friday, 5 July 2013

Retinoids

The retinoids are medications that are derivatives of Vitamin A. They are the treatment of choice for comedonal acne, or whiteheads and blackheads.
Tretinoin
* The best-known topical retinoid
* Marketed as Retin-A, Avita, and Renova
* Also available as a generic
* Available as a cream (0.025%, 0.05%, and 0.1%), gel (0.01% and 0.025%), and a liquid (0.05%)
* Creams are less potent than gels, which are less potent than the liquid
* Breaks down chemically in the presence of benzoyl peroxide, therefore cannot be applied at the same time of the day
* High incidence of skin irritation and precautions must be taken when starting
* Increases risk of sunburn
* A new formulation Retin-A Micro 0.1% releases tretinoin over a longer period of time and is less irritating.

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